Major Research Themes in the Discipline of Diabetes, Nutrition and Metabolic Diseases

Integrative approach to obesity and insulin resistance syndrome

• Assessment of the prevalence of obesity and atypical cardiometabolic phenotypes of obesity in the adult population of Romania
• Identification of molecular mechanisms involved in the pathogenesis of obesity
• Impact of obesity-induced insulin resistance and adipocytokines on liver histology
• Role of the endocannabinoid system in the pathogenesis of obesity
• Therapeutic perspectives in obesity management

Integrative approach to diabetes and chronic diabetic complications

• Assessment of the prevalence of diabetes and prediabetes in the adult population of Romania
• Innovative assessment methods in type 1 diabetes mellitus - 1H-NMR spectroscopy
• New perspectives on chronic complications of diabetes
• Chronic kidney disease: prevalence and glycaemic variability
• Approach to diabetic periodontal disease

Integrative approach to dyslipidaemia

• Assessment of the prevalence of dyslipidaemia in the adult population of Romania
• New insights into the study of the impact of dyslipidaemia on endothelial progenitor cells

Research directions

• Insulin receptor isoforms - crosstalk between insulin resistance and cancer phenotype

• Insulin resistance and hepatic steatosis in type 1 diabetes mellitus and their association with diabetic chronic complications

• New approaches in modulating the GLP-1/GLP-2 axis: common link between metabolic diseases and inflammatory bowel diseases